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Alex Karev (Justin Chambers) deals with the fallout of his decision to tell Owen about Meredith altering the Alzheimer's trial, and becomes an outcast by the other residents.
Teddy Altman (Kim Raver) marries Henry Burton (Scott Foley), who later dies of a heart condition, leaving her devastated. Loretta Devine garnered critical acclaim for her portrayal of Adele Webber and earned numerous nominations including the Primetime Emmy Awards for Outstanding Guest Actress in a Drama Series and the Critics' Choice Television Awards. won Outstanding Supporting Actor at the NAACP Image Awards, and Chandra Wilson and Sandra Oh both received nominations for Outstanding Actress in a Drama.
April is named the new Chief resident, and struggles throughout the season to be taken seriously by the other residents, while also developing a much deeper friendship with Jackson until she finally has sex with him in episode 21, "Moment of Truth." Throughout the season, the fifth year surgical residents (Meredith, Cristina, Alex, April, and Jackson) prepare for their boards.Their marital unrest, as well as Meredith's professional fallout, threatens to destroy their chances of adopting Zola, but they eventually get full custody of her in episode 10, "Suddenly." After discovering the reason Meredith tampered with the trial was in attempt to deliver the drug to Adele and potentially cure her Alzheimer's, Richard takes the blame, and steps down as Chief of Surgery.Owen is named the new Chief of Surgery (episode 3, "Take the Lead"), which leaves Miranda angry.For the 38th People's Choice Awards, the show was nominated for Favorite TV Drama, and Ellen Pompeo and Patrick Dempsey were respectively nominated for Favorite TV Drama Actress and Favorite TV Drama actor.In season 8, Meredith and Derek try to save their marriage after the fallout due to Meredith's tampering of the Alzheimer's trial in Season 7.